An Overview on Nano Niosomes: As an Optimistic Drug Delivery System in Targeted Drug Delivery
نویسندگان
چکیده
Targeted drug-delivery systems are used for the administration of pharmaceutical medicament enables localization drugs to diseased sites. Different types uses carriers, like immunoglobulins, serum proteins, synthetic polymers, liposomes, nanoparticle and microspheres. Niosomes an emerging type novel vesicular systems. Now they being fervent explored as potential carriers targeted drug delivery. In addition conventional, oral, parenteral routes, liable be delivered by ocular, transdermal, vaginal, inhalation routes. Nano-niosomes non-ionic surfactants based vesicles that biodegradable, relatively nontoxic, more stable inexpensive than liposomes. Other component, such cholesterol, can give rigidity niosomes structure. The unique structure niosomes, with their bilayer lamellae assembled nonionic surfactants, is able increase bioavailability a predetermined area period. amphiphilic nature promotes efficiency in encapsulating hydrophobic or hydrophilic drugs. These not only transport pharmacological agents target site disease site, avoiding normal tissues reducing toxicity rest body, but also protect from degradation, half-life, payload solubility reduce renal clearance. This present review describe overview formulation aspects, structure, advantages, disadvantages, method preparation well some general observations on niosomes.
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ژورنال
عنوان ژورنال: Journal of pharmaceutical research international
سال: 2022
ISSN: ['2456-9119']
DOI: https://doi.org/10.9734/jpri/2022/v34i34a36142